logo for MGH Biomedical Informatics Core

MIND Informatics develops and applies integrative computational methods in biomedical and brain research, working with leading clinicians and researchers to understand and cure neurological disorders.

MGH Biomedical Informatics Core

The MGH Biomedical Informatics Core (MGH BMIC) - part of MIND Informatics - serves the information management and analysis needs of the MGH/Partners/Harvard research community as well as non-profit organizations and industry. MGH BMIC has significant expertise in classical biomedical informatics (computational biology, biomedical and clinical databases, data integration), as well as scientific social media, in which we are an internationally recognized leader. We leverage re-usable tools developed by the group, along with open source software in a cost-effective manner.

We offer the following services:

Scientific Community Websites

We develop online scientific community websites with extensive use of social media for research communities, departments and institutions. Features include discussion forums; news and commentaries; weekly paper collection with automatic nightly feeds from Pubmed; member directory and enhanced search capabilities. Graphic design and hosting is included in the service. We leverage a reusable platform, the Science Collaboration Framework (SCF) for this service. SCF has previously been used for several websites, notably:
Pain Research Forum, Multiple Sclerosis Discovery Forum and StemBook.

Bioinformatics Analysis

Our group provides bioinformatics and statistical analyses. Sample analyses include in-silico target identification, database and literature searches, protein annotation, microarray analysis, and next-generation sequencing pipeline execution. Free consultation with an estimate of the work is provided to the researcher. Services include supervision by a senior bioinformatician and all required computing infrastructure.

Biomedical Data Management Solutions

We build biomedical data management solutions for complex genomics and drug discovery assay data. Researchers can share their experiments and data; annotate the biomaterials and assays with controlled vocabulary terms and perform initial data analysis. Enhanced search and browse capabilities are provided with the software. We leverage the eXFrame platform for this service, which was used to develop Stem Cell Commons.

Bioinformatics Training

We provide hands-on bioinformatics training sessions to small groups of researchers. Topics include basic statistics, design of experiments, micro-array analysis, next-generation sequencing analysis, and use of common bioinformatics tools, etc.  Content and level will be tailored to the audience. Training room, equipment and materials will be provided.

Knowledge-Base Development

We develop custom knowledge bases of diseases. Intense literature scanning is done by subject matter specialists and significant research hypothesis, claims and their evidence is curated in a semantic-web based platform for enhanced searches and interoperability with other knowledge repositories. All claims are linked to relevant proteins, organisms and cells for easy-to-use lookups.

Custom Informatics Solutions

Our group can support various software solution needs including information management, database building, website development or maintenance for your group. Please contact us for project estimates.