The Massachusetts Alzheimer Disease Research Center (MADRC) is one of the world's leading centers for research into the causes, treatment and potential cures for Alzheimer Disease (AD), a devastating neurodegenerative disorder affecting more than 25 million people worldwide. A collaboration between researchers at the Massachusetts General Hospital and Brigham and Women's Hospital, MADRC is funded by a National Institute on Aging P-50 award, as well as private philanthropy. MADRC is one of the oldest research centers in the NIA program.
MIND Informatics co-directs and manages the MADRC Data and Statistics Core, in collaboration with Prof. Rebecca Betensky (Harvard School of Public Health) and collaborates closely with clinician-researchers in the MADRC Clinical Core, led by Profs. Deborah Blacker and Teresa Gomez-Isla.
We maintain a >25-year longitudinal clinical research database with detailed demographic and subject testing data on AD patients seen at our Center, who kindly donate their time and effort to participate in psychometric, biomarker, genomic, brain imaging, and pharmacological studies. This data repository serves as a central cohort-selection resource for collaborative projects in which MADRC participates, including ongoing clinical trials of promising therapeutics.
Our current data management platform is based on LAVA, originally developed and launched at the UCSF Memory and Aging Center, and now a collaborative software development effort between UCSF, Emory University, MADRC (MGH/BWH/Harvard) and UC Davis.
If you manage an NIA P-50 Alzheimer Center and wish to participate in the LAVA collaboration or other joint efforts in clinical informatics, feel free to contact us.